Definitely yes. Astigmatic correct will make the lenses thicker than those without astigmatism corrections. If the axis correction is at 90 degrees and the astigmatism is high, then the lens thickness will show when you view the glasses from the side. If the axis correction is at 180 degrees, you probably will not be able to see it as the thickness will show from the top and bottom, which is usually being cut off to fit into the glasses.However, if you could choose a right frame such as plastic or actate frame as well as high index aspheric lenses, it will hide the lenses thickness in some degree.